[PDF.94jf] The Role of Regulatory T Cells in Bone Homeostasis: Linking Cells from the Immune System with Bone Cells

The Role of Regulatory T Cells in Bone Homeostasis: Linking Cells from the Immune System with Bone Cells

[PDF.il29] The Role of Regulatory T Cells in Bone Homeostasis: Linking Cells from the Immune System with Bone Cells

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 |  2010-04-08 | Original language:English | PDF # 1 |  8.66 x.25 x5.91l,.37 | File type: PDF | 108 pages

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||About the Author|Mario Zaiss finished his Ph.D. thesis at the Medical Clinic 3, Immunology and Rheumatology at the University of Erlangen-Nuremberg in 2009.

In summary, our data open a new perspective in the interaction between the immune system and the skeleton. The central concept of osteoimmunology that inflammatory T cell subsets such as activated Th1 cells and Th17 cells drive bone loss is now enriched by the concept that immune homeostasis is tightly linked to bone homeostasis. Thus, a key mechanism of immune regulation, the naturally occurring Foxp3+ regulatory T cells, transduces its favourable role in immune balance...

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