[PDF.57re] The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research)
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The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research)
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[PDF.eu63] The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research)
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| #12642131 in Books | 2007-12-10 | Original language:English | PDF # 1 | 9.50 x7.00 x.50l,.0 | File type: PDF | 192 pages||From the Back Cover||The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell–AP
This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance induction; and mechanisms maintaining dominant tolerance.
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