[PDF.67sq] T Cell Hybridomas: A Workshop at the Basel Institute for Immunology (Current Topics in Microbiology and Immunology)

T Cell Hybridomas: A Workshop at the Basel Institute for Immunology (Current Topics in Microbiology and Immunology)

[PDF.fj67] T Cell Hybridomas: A Workshop at the Basel Institute for Immunology (Current Topics in Microbiology and Immunology)

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 |  Springer |  2011-11-01 | Original language:English | PDF # 1 |  9.61 x.64 x6.69l,.99 | File type: PDF | 264 pages

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For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblasts (1) or lymphomas (2), both of which do not produce Ig, and with Ig­ producing myelomas (3) or human blood lymphocytes (4). Kohler and Milstein (5) fused a myeloma with spleen cells from immunized mice. Up to 10% of the hybrids obtained secreted antibodies specific for ...

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