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Superantigens (Current Topics in Microbiology and Immunology)

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 |  2012-05-26 |  2012-05-26 | Original language:English | PDF # 1 |  9.25 x.36 x6.10l,.50 | File type: PDF | 137 pages

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This volume of Current Topics in Microbiology and Immunology is concerned with a class of molecules that are the most potent polyclonal stimulators of T lymphocytes of several species. These molecules have been named "superantigens" because they use a mechanism of T cell stimulation closely mimicking MHC-restricted recognition of specific antigen: they act on variable parts of T cell antigen receptors and are presented by MHC class II molecules. Prototypes of these molec...

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